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Gastrointestinal, Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is defined as chronic symptoms or mucosal damage produced by the abnormal reflux in the esophagus.
One in 10 Americans experiences heartburn symptoms at least once a week. Heartburn has different triggers, including certain foods, medications, obesity, or even stress. Acid reflux is common, but chronic acid reflux (Gastroesophageal Reflux Disease) can become a real problem.
At the entrance to the stomach is a valve called lower esophageal sphincter (LES). The LES should close as soon as food enters the stomach so that no food can splash back up into the esophagus, however, if the LES does not close properly or if it opens often, stomach acid can move into the esophagus and cause heartburn. There are various causes including hiatal hernias, eating foods containing high amounts of acid (citrus, coffee, tomato, chocolate, or spicy or fatty foods), and drinking alcohol.
Typically, GERD is treated with prescription or over the counter medications. These prescriptions can have side effects such as nausea, headache, diarrhea, gas, bloating, constipation, and stomach pain. Cannabinoids can be effective against these side effects, but it can also improve acid reflux in general.
It has been found that “Activation of cannabinoid receptors (CB(1), CB(2) and GPR(55)) produces analgesic effects in several experimental pain models, including visceral pain arising from the gastrointestinal tract” in one study at AstraZeneca R&D Mölndal in Sweden.
At the Department of Experimental Pharmacology at the University of Naples in Italy also conducted research on gastrointestinal problems: “Salvinorin A, the active component of the hallucinogenic herb Salvia divinorum, inhibits intestinal motility through activation of kappa-opioid receptors (KORs). However, this compound may have target(s) other than the KORs in the inflamed gut. Because intestinal inflammation upregulates cannabinoid receptors and endogenous cannabinoids, in the present study we investigated the possible involvement of the endogenous cannabinoid system in salvinorin A-induced delay in motility in the inflamed gut.” The study concluded, “The inhibitory effect of salvinorin A on motility reveals a functional interaction between cannabinoid CB(1) receptors and KORs in the inflamed-but not in the normal-gut in vivo.”
Raymond C. Dabney Raymond C. Dabney This is exactly why I wrote this statement.
We will probably put out the July 1, 2020 Edition after the Fourth...Raymond C. Dabney Raymond C. Dabney This is exactly why I wrote this statement.
We will probably put out the July 1, 2020 Edition after the Fourth of July, depending how today goes.
Our shares are not being issued tomorrow, at this point, I think we will have a VIRTUAL VIDEO PARTY on that Day.
Things have changed dramatically, everywhere, our PROJECTS have Grown immensely, at this point my Best Guess is September 1, 2020; "All Our" shares will be issued and still on TARGET for June 1, 2021 initial filings for Share Trading options.
*** There is so much work to be done, Step by Step.
*** AND we are beta launching our technology right now, so it has been EXTRA.
This is exactly why I wrote this statement.
I think in Life we are supposed to Accept the Things we can Not Change, and Change the Things we Can.
This is MUCH better than hammering your Soft Head against a NEGATIVE BRICK wall. We have had nothing but, Acceptance and Change.
Sometime you need to CHANGE your Path unexpectedly to find your way Around that BRICK wall.
And Then, we still Succeed, no matter what, no matter how long. Period.
If I could CHANGE a lot of things I would.
Oh yes, as I have said a few time now; There is some Good Change coming right around the corner
Raymond Show less
2 days ago
Raymond C. Dabney Raymond C. Dabney Going to need to open the doors and let everyone in the website soon. Been saying that for a minute and been waiting to get this work out of the way. As we can see just by opening the doors causes Great Work. Good thing EVERYONE can read EVERYTHING without being logged in.
Here we go! This is when the fun starts, we will be PUSHING HARD to Surpass 1 Million Members, TV/Media and some good Surprises will help that out.
We are certainly "Bringing it ALL Together".
2 days ago
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