Traumatic brain injury occurs when an external mechanical force causes brain dysfunction.
Traumatic brain injury usually results from a violent blow or jolt to the head or body. An object penetrating the skull, such as a bullet or shattered piece of skull, also can cause traumatic brain injury.
Mild traumatic brain injury may cause temporary dysfunction of brain cells. More serious traumatic brain injury can result in bruising, torn tissues, bleeding and other physical damage to the brain that can result in long-term complications or death. - mayoclinic.org
In 2010 the US Centers for Disease Control and Prevention calculated the rate of traumatic brain injury emergency visits to be 823.7 per 100,000 visits.
Mild traumatic brain injuries usually require no treatment other than rest and over-the-counter pain relievers to treat a headache. However, a person with a mild traumatic brain injury usually needs to be monitored closely at home for any persistent, worsening or new symptoms. He or she also may have follow-up doctor appointments.
Emergency care for moderate to severe traumatic brain injuries focuses on making sure the person has an adequate oxygen and blood supply, maintaining blood pressure, and preventing any further injury to the head or neck. This can be accomplished with a variety of medications (diuretics, anti-seizure drugs, coma-inducing drugs) or surgical techniques. - mayoclinic.org
Evidence for and Proposed Mechanism of Action of Cannabinoids
Animal models have shown cannabinoids to be neuroprotective after trauma, demonstrating reduced glutamate excitotoxicity, free radical damage, and inflammatory response.3, 4 Other animal studies have shown decreased vasospasm and inhibition of tumor necrosis factor-a, both of which are associated with neuroprotection.5, 6
Aditionally a 3-year retrospective review of registry data at a surgical intensive care unit of patients sustaining traumatic brain injury demostrated that a positive THC screen is associated with decreased mortality in these adult patients.
1. Yoles E, Belkin M, Schwartz M. HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy. J Neurotrauma 1996;13:49–57.
2. Brewter ME, Pop E, Foltz RL, et al. Clinical pharmacokinetics of escalating IV doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers. Int J Clin Pharmacol Ther 1997;35: 361–5.
3. Durmaz R, Ozsandik A, Sahintu¨rk V, et al. Dexanabinol prevents development of vasospasm in the rat femoral artery model. Neurosurg Rev 2008;31:215–23.
4. Brewter ME, Pop E, Foltz RL, et al. Clinical pharmacokinetics of escalating IV doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers. Int J Clin Pharmacol Ther 1997;35: 361–5.
5. Nguyen et al. Effect of Marijuana Use of Outcomes in TBI. Presented at the 25th Annual Scientific Meeting of the Southern California Chapter of the American College of Surgeons, January 17–19, 2014
Question: Why doesn't anyone (Broker, Transfer agent...) know what is happening every "Step" of the way ??
Answer: Because they are waiting on "Step...Question: Why doesn't anyone (Broker, Transfer agent...) know what is happening every "Step" of the way ??
Answer: Because they are waiting on "Step by Step" instructions from the Company, just like everyone else.
Question: Why is this so tough to comprehend ??
Answer: Because some people do not want the Company to Succeed.
Line item: “Domicile Changes”. This is the short form statement for our company legal re-structure work when you have different operations in different geological locations or different jurisdictions or different Countries and so on, if you will. Our corporate services groups advises us of our options to accomplish our goals on a local and international basis, this is the main work no one sees behind the scenes.
Usually it’s our management team and our service providers running around, communicating and completing all actions “Steps” required to complete the new share issuances in all jurisdictions. Primarily we are dealing with; resolutions, notaries, legal opinions, fedex, dhl, different government services and agencies, transfer agents, back and forth with EVERYONE at the same time or concurrently, depending on what “Step” we are on until it all gets done.
*** Considering what we have accomplished thus far, (Harvard Award, Killing Cancer with Harvard, more historical clinical studies, and strong FDA initiatives targeting so many critical ailments, and so much more…).
All this “Success” that we have accomplished thus far makes the time it takes to complete all these corporate “Steps” NOTHING compared to the rewards we all receive with our “continued Success”. Hence, the “paid monster” attacks (acting like shareholders) that want us to fail.
Even the SEC wants to see us Succeed, and they are NOT even shareholders!!! We are Truly Blessed, about to be very Happy, and back on the Highway!
We are good and we are almost done, it’s just taking way longer than expected, new info and changes, which are frustrating at best, however sometimes it’s in our favor and that’s the BEST Part. Things do change along the way, legal pathways, new information, economic and demographic, sometimes even new circumstances around the world changes things, so we make sure we stay fluid and make the proper adjustments to accommodate the "Steps" until we complete our Goals.
Stay Strong, Be Positive, don’t let the negative or even nasty people mess stop you from anything you want to accomplish, “Ten times out of Ten” they are just Jealous in the end.
Stay Safe and Stay Home everyone, this nasty virus mess seems to be teetering at the top right now, this thing is wild, but beatable. Stay healthy, Vitamin C as a base seems to be working for me, God willing, everything else is about basic medicinal survival. Under those circumstances please make your medical choices with your family Doctor.
Stay Strong and God Bless.
Raymond Show more