Adult acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. This type of cancer usually gets worse quickly if it is not treated. It is the most common type of acute leukemia in adults. AML is also called acute myelogenous leukemia, acute myeloblastic leukemia, acute granulocytic leukemia, and acute nonlymphocytic leukemia.
Leukemia may affect red blood cells, white blood cells, and platelets.
Normally, the bone marrow makes blood stem cells (immature cells) that become mature blood cells over time. A blood stem cell may become a myeloid stem cell or a lymphoid stem cell. A lymphoid stem cell becomes a white blood cell.
A myeloid stem cell becomes one of three types of mature blood cells:
Red blood cells that carry oxygen and other substances to all tissues of the body.
White blood cells that fight infection and disease.
Platelets that form blood clots to stop bleeding.
In AML, the myeloid stem cells usually become a type of immature white blood cell called myeloblasts (or myeloid blasts). The myeloblasts in AML are abnormal and do not become healthy white blood cells.
Sometimes in AML, too many stem cells become abnormal red blood cells or platelets. These abnormal white blood cells, red blood cells, or platelets are also called leukemia cells or blasts. Leukemia cells can build up in the bone marrow and blood so there is less room for healthy white blood cells, red blood cells, and platelets. When this happens, infection, anemia, or easy bleeding may occur. The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (brain and spinal cord), skin, and gums.
AlveeEvidence suggests that cannabis shows potential as a viable treatment option for leukemia. One of the major cannabinoids found in cannabis,...Evidence suggests that cannabis shows potential as a viable treatment option for leukemia. One of the major cannabinoids found in cannabis, tetrahydrocannabinol (THC), has been shown to induce apoptosis, or death, of leukemia cells (Powles, et al., 2005) (Murison, et al., 1987) (Scott, Shah, Dalgleish & Liu, 2013). Another major cannabinoid, cannabidiol (CBD), has also been shown to significantly decrease tumor burden and increase the death of cancerous leukemia cells (Gallily, et al., 2003) (McKallip, et al., 2006) (Scott, Shah, Dalgleish & Liu, 2013). Evidence has shown that a greater dose of cannabis is associated with a greater apoptosis response (Gallily, et al., 2003). One study found that combining THC treatment with additional established cytotoxic agents could further enhance leukemia cancer cell death (Liu, et al., 2008). These findings have caused researchers to conclude that cannabis “may be a novel and highly selective treatment for leukemia” (McKallip, et al., 2006).Show more3 years ago
Osaruname Osayi-OsazuwaThis is one of the many reasons why I advocate for cannabinoids to be legalized throughout the United States. Cancer runs on both sides of my family...This is one of the many reasons why I advocate for cannabinoids to be legalized throughout the United States. Cancer runs on both sides of my family as well as other autoimmune diseases such as diabetes. Furthermore, other autoimmune diseases have been linked to cancer. Show more2 years ago
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